When ANA is positive, SSA along with other antibodies are ordered to determine the underlying disease.
SSA or Anti-Ro are antinuclear antibodies that are seen in the following conditions:
Sjogren’s Syndrome
Systemic Lupus
Subacute Cutaneous Lupus
Photosensitive Dermatitis
SSA Antibodies are rare in other connective tissue diseases and rheumatoid arthritis.
SSA presence is associated with:
Primary Sjogren’s Syndrome
Neonatal Lupus
Congenital Heat Block
Vasculitis
Photosensitivity
Interstitial Lung Disease
Complement deficiencies
HLA-DR3